Join CafeMom Today! Autism Spectrum Disorder: Treatments: Which came first? The autism or the seizures?

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Thursday, July 12, 2012

Which came first? The autism or the seizures?

Which came first, the autism or the seizures?  Many people with autism have seizures, but could seizures early in life lead to autism?  My daughter had her first seizure at 4 months and several very lengthy seizures at around 8 months.

PLoS ONE: The Interaction between Early Life Epilepsy and Autistic-Like Behavioral Consequences: A Role for the Mammalian Target of Rapamycin (mTOR) Pathway
Early life seizures can result in chronic epilepsy, cognitive deficits and behavioral changes such as autism, and conversely epilepsy is common in autistic children. We hypothesized that during early brain development, seizures could alter regulators of synaptic development and underlie the interaction between epilepsy and autism. 

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